Trenbolone-150 (Trenbolone Acetate)
Trenabolon-150 for intramuscular injection, contains Trenbolone Acetate. Trenbolone Acetate is a fast acting injectable steroid.
To increase its effective half-life, trenbolone is not used in an unrefined form, but is rather administered as trenbolone acetate ,enanthate or Hexahydrobenzylcarbonate. Trenbolone is then produced as a metabolite by the reaction of these compounds with the androgen receptor.
Bodybuilders have been known to use the drug in order to increase body mass more effectively than by weight training alone. A normal bodybuilding dosage can range from 200 mg/week up to 1400 mg/week. Due to the relatively short metabolic half-life of trenbolone acetate, dosages should commonly be split into injections at least once every two days. Trenbolone enanthate can be injected once a week.
The 2006 book Game of Shadows alleges that baseball superstar Barry Bonds used this drug in 2001, when he set the current single-season home run record.
Trenbolone compounds have a binding affinity for the androgen receptor three times as high as that of testosterone. Once metabolised, the drugs have the effect of increasing nitrogen uptake by muscles, leading to an increase in the rate of protein synthesis. It also has the secondary effects of stimulating appetite, reducing the amount of fat being deposited in the body, and decreasing the rate of catabolism. Trenbolone has proven popular with anabolic steroid users as it is not metabolised by aromatase or 5α-reductase into estrogenic compounds such as estradiol, or into DHT. This means that it also does not cause any water retention normally associated with highly androgenic steroidal compounds like testosterone or methandrostenolone. It is also loved by many for the dramatic strength increases commonly experienced with it. Some short-term side effects include insomnia, high blood pressure, increased aggression and libido. However, since women will suffer virilization effects even at small doses, this drug should not be taken by a female. Urban wisdom/myth in bodybuilding culture, states that the use of the drug over extended periods of time can lead to kidney damage. The kidney toxicity has not yet been proven, and scientific evidence supporting the idea is suspiciously absent from the bodybuilding community that perpetuates this idea. The origin of this myth most likely has to do with the rust colored oxidized metabolites of trenbolone which are excreted in urine and often mistaken for blood. After Schänzer (Clin Chem 1996; 42(7): 1001-1020, Metabolism of anabolic androgenic steroids) trenbolone and 17epi-trenbolone are both excreted (in urine) as conjugates that can be hydrolyzed with beta-glucuronidase. This implies that trenbolone leaves the body as beta-glucuronides or sulfates, that means mostly non metabolized.
Trenbolone
Trenbolone was first described in 1967. This is an extremely strong anabolic steroid, 19-nor modification of testosterone, but with by five times stronger both anabolic and androgenic activity. It is one of the strongest injectable anabolic steroids ever commercially manufactured.
Among athletes, this steroid is highly valued for its ability to increase muscle hardness, definition, and raw strength, without unwanted water retention and fat mass gains. It is considered a drug of choice for contest bodybuilders, yet remains very popular with recreational users simply looking to refine their physiques.
What makes Trenbolone so anabolic? Numerous factors come into play. One of the most valuable of all these features is undoubtedly its ability to increase the nutrient efficiency, in other words, the nutritional value of every gram of proteins, fats and carbohydrates you eat become more valuable, they are assimilated much more efficiently.
In addition to increasing the nutrient efficiency, trenbolone can as no other drug stimulate the following most typical activities of anabolic steroids: acceleration of protein synthesis and maintenance of positive nitrogen balance. Protein synthesis determines how rapidly the body will build muscles, at that, the higher the nitrogen balance is the more proteins will be built.
The next big advantage: trenbolone greatly increases the level of the extremely anabolic hormone IGF-1 (insulin-like growth factor) within muscle tissue (up to 200%). And, it’s worth noting that not only does it increase the levels of IGF-1 in muscle over two fold, it also causes muscle satellite cells to be more sensitive to IGF-1 and other growth factors. The amount of DNA per muscle cell may also be significantly increased.
One more plus of trenbolone is its ability to an incredible degree increase the production of red blood cells responsible for transporting oxygen in the bloodstream. The more red blood cells are in blood, the better is oxygen saturation of organs, including muscles, which is very important for the development of muscular endurance. In addition, trenbolone promotes glycogen replenishment considerably improving recovery.
It also has the ability to significantly reduce the production of anti-anabolic (muscle destroying) glucocorticoid hormones, in particular cortisol.
However, it's incredible mass building effects do not end there. This steroid firmly, much stronger than testosterone, binds directly to androgen receptors and thus directly stimulates fat burning. Along with such a quantity of benefits, trenbolone has also side effects. Trenbolone is a 19-nor modification of testosterone, which makes it progestogenic similar to nandrolone, hence, prolactin inhibitors (cabergoline) shall be used, if required.
CAUTION: Tamoxifen on trenbolone cycles and on PCT (post cycle therapy) can strengthen progestogenic activity of trenbolone, so it should not be used. Clomid or toremifene are recommended for PCT after all 19-nor testosterone modifications.